Ammonium Chloride → Sodium 5-Amino-2-(2-methoxyethyoxy)benzenesulfonate

HRID 1389524Notes

Reaction equation

HRID 1389524 reaction equation
[CH3:1][O:2][CH2:3][CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([N+:12]([O-])=O)=[CH:8][C:7]=1[S:15]([O-:18])(=[O:17])=[O:16].[Na+:19].[Cl-].[NH4+]>O>[NH2:12][C:9]1[CH:10]=[CH:11][C:6]([O:5][CH2:4][CH2:3][O:2][CH3:1])=[C:7]([S:15]([O-:18])(=[O:17])=[O:16])[CH:8]=1.[Na+:19]

Participants

4

Reactant 2

HCID 25517Ammonium ChlorideHCID 101686797CID 101686797

Product 1

HCID 23709232Sodium 5-Amino-2-(2-methoxyethyoxy)benzenesulfonate

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture solution of 30 g of sodium 2-(2-methoxyethoxy) -5-nitrobenzenesulfonate, 30 g of reduced iron, 0.6 g of ammonium chloride and 60 ml of water was heated at 80° to 85° C. with stirring for 2 hours. After completion of the reaction, the insoluble materials were removed by filtration, 200 ml of isopropyl alcohol was added to the filtrate and the mixture was cooled with ice. The crystals thus precipirated were collected by filtration, washed with 50 m of isopropyl alcohol and air-dried. Yield: 23 g. Melting Point: over 250° C.

Workup

  1. customAfter completion of the reaction
  2. customthe insoluble materials were removed by filtration, 200 ml of isopropyl alcohol
  3. additionwas added to the filtrate
  4. temperaturethe mixture was cooled with ice
  5. filtrationThe crystals thus precipirated were collected by filtration
  6. washwashed with 50 m of isopropyl alcohol
  7. customair-dried
  8. customover 250° C.

Sources & evidence

ORD record
ord-d28f809d6ea644029134d2645b173ad8
Source dataset
uspto-grants-1981_01
Patent number
US04245028

Reaction notes

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