HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1389532Generated: November 1, 2026
HCID 12690102, compound → HCID 20296477, compound
https://huagongshe.com/reaction/1389532
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | HCID 12690102 | HCID 12690102 | — |
| Reactant | HCID 20296478 | HCID 20296478 | — |
| Reactant | HCID 20296480 | HCID 20296480 | — |
| Reactant | HCID 20296483 | HCID 20296483 | — |
| Reactant | HCID 20296485 | HCID 20296485 | — |
| Product | HCID 20296477 | HCID 20296477 | — |
| Product | HCID 20296481 | HCID 20296481 | — |
| Product | HCID 20296488 | HCID 20296488 | — |
| Product | HCID 20296493 | HCID 20296493 | — |
Reaction Steps
Following essentially the same procedure but substituting 3-[(o-methylphenyl)methyl]-1-azabicyclo[2.2.2]-octane-4-carboxylic acid, 3-[(p-bromophenyl)methyl]-1-azabicyclo[2.2.2]octane-4-carboxylic acid, 3-[(m-isopropylphenyl)methyl]-1-azabicyclo[2.2.2]octane-4-carboxylic acid, and 3-[(o-chlorophenyl)methyl]-1-azabicyclo[2.2.2]octane-4-carboxylic acid for the 3-(phenylmethyl)-1-azabicyclo[2.2.2]octane-4-carboxylic acid above results in the formation of 9-methyl-3,4,10,10a-tetrahydro-2,4a-ethanobenz[g]isoquinolin-5(1H)-one, 7-bromo-3,4,10,10a-tetrahydro-2,4a-ethanobenz[g]isoquinolin-5(1H)-one, 8-isopropyl-3,4,10,10a-tetrahydro-2,4a-ethanobenz[g]isoquinolin-5(1H)-one, and 9-chloro-3,4,10,10a-tetrahydro-2,4a-ethanobenz[g]isoquinolin-5(1H)-one as their hydrochloride salts, respectively.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04244955 |
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| Source dataset | uspto-grants-1981_01 |
|---|
| ORD ID | ord-8e6c083ac4b74bc9ae4fe2eeeee4c17e |
|---|
| Source note | uspto-grants-1981_01 |
|---|
