Sulfuric Acid → HCID 86737435, compound

HRID 1389537Notes

Reaction equation

HRID 1389537 reaction equation
[SH:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][CH:3]=1.[C:9]([O:12]C(=O)C)(=[O:11])[CH3:10].S(=O)(=O)(O)O>>[C:9]([OH:12])(=[O:11])[CH3:10].[C:9]([OH:12])(=[O:11])[CH3:10].[SH:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][CH:3]=1

Participants

4

Reactant 3

HCID 1118Sulfuric AcidHCID 7918Acetic AnhydrideHCID 2401474-Mercaptophenol

Product 1

HCID 86737435HCID 86737435, compoundYield 80.6%

Conditions

Temperature
100 °C

Procedure

126.17 grams (1 mole) of p-mercaptophenol is added into 714.6 grams of acetic anhydride with 5 cc. of sulfuric acid. After the resulting mixture is heated at 100° C. for 2 hours, it is allowed to cool and is poured into 3 l. of water in order to precipitate the product. The solid is filtered, recrystallized from 3.5 l. of hexane and dried overnight at 100° C. to yield 198.5 grams of 4-mercaptophenol diacetate which has a melting range of 73-75° C.

Workup

  1. temperatureto cool
  2. additionis poured into 3 l
  3. customof water in order to precipitate the product
  4. filtrationThe solid is filtered
  5. customrecrystallized from 3.5 l
  6. dry with materialof hexane and dried overnight at 100° C.

Sources & evidence

ORD record
ord-699d87ecf2344d4a8ddfc1cc9aacaff6
Source dataset
uspto-grants-1981_01
Patent number
US04245084

Reaction notes

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