Aluminum(III) Chloride → Pyridine, 2,3,5-trichloro-

Participants

Reaction Conditions

Reaction Steps

13.6 g of 2,4,4-trichloro-4-formylbutyronitrile obtained according to (a), with the addition of 1.0 g of AlCl3, is heated in an enamel autoclave for 1 hour at 60° C. The dark crude product is afterwards distilled with steam, in the process of which the 2,3,5-trichloropyridine precipitates, in the distillate, in the form of white crystals. The yield is 9.1 g (83% of theory) of 2,3,5-trichloropyridine, m.p. 49°-50° C.

Provenance & Evidence