Potassium Hydroxide → 2-[(2-Amino-2-phenylethyl)amino]ethan-1-ol

HRID 1389549Notes

Reaction equation

HRID 1389549 reaction equation
[OH:1][CH2:2][CH2:3][N:4]1[CH2:8][CH:7]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[N:6]=C1C.[OH-].[K+]>C(O)C.O>[NH2:6][CH:7]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[CH2:8][NH:4][CH2:3][CH2:2][OH:1]

Participants

5

Reactant 2

HCID 14797Potassium HydroxideHCID 20551606HCID 20551606, compound

Product 1

HCID 205516032-[(2-Amino-2-phenylethyl)amino]ethan-1-ol

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 962WaterSolvent

Procedure

The hydroxyethylmethylphenylimidazoline produced in Example II in the amount of 30 g and 60 g potassium hydroxide, in 150 ml ethanol and 40 ml water, are refluxed for 24 hours. The solution is then concentrated by removal of the ethanol, and the residue is taken up in 50 ml of water.

Workup

  1. concentrationThe solution is then concentrated by removal of the ethanol

Sources & evidence

ORD record
ord-c77f9b920320408fb95ad3539cfa473d
Source dataset
uspto-grants-1981_01
Patent number
US04245102

Reaction notes

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