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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1389552Generated: October 29, 2026

1-(2-Methoxyethyl)-4-phenylimidazolidine-2-thione → Levamisole

https://huagongshe.com/reaction/1389552

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Methoxyethyl)-4-phenylimidazolidine-2-thioneHCID 12803437—
SolventHydrochloric AcidHCID 313—
SolventWaterHCID 962—
ProductLevamisoleHCID 26879—

Reaction Steps

The 1-2(methoxyethyl)-4-phenylimidazolidin-2-thione product of Example VII in the amount of 0.78 g is suspended in 50 ml concentrated aqueous hydrochloric acid and maintained with stirring at 70°-75° C. for four hours. The solution is then cooled at room temperature and diluted with 50 ml water.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04245102
Source datasetuspto-grants-1981_01
ORD IDord-aed09b4c53204ea7a74426f7309b1b0b
Source noteuspto-grants-1981_01