3-Carbamoyloxymethyl-7-amino-3-cephem-4-carboxylic acid → HCID 131712052, compound

HRID 1389610Notes

Reaction equation

HRID 1389610 reaction equation
[CH3:1][CH:2]([CH:6]([S:9]([C:11]1[CH:16]=[CH:15][C:14]([OH:17])=[CH:13][CH:12]=1)=[O:10])[CH2:7][CH3:8])[C:3]([OH:5])=O.[NH2:18][CH:19]1[C:34](=[O:35])[N:21]2[C:22]([C:31]([OH:33])=[O:32])=[C:23]([CH2:26][O:27][C:28](=[O:30])[NH2:29])[CH2:24][S:25][C@H:20]12>>[CH3:1][CH:2]([CH:6]([S:9]([C:11]1[CH:16]=[CH:15][C:14]([OH:17])=[CH:13][CH:12]=1)=[O:10])[CH2:7][CH3:8])[C:3]([NH:18][CH:19]1[C:34](=[O:35])[N:21]2[C:22]([C:31]([OH:33])=[O:32])=[C:23]([CH2:26][O:27][C:28](=[O:30])[NH2:29])[CH2:24][S:25][C@H:20]12)=[O:5]

Participants

3

Reactant 2

HCID 127847593-Carbamoyloxymethyl-7-amino-3-cephem-4-carboxylic acidHCID 53734739HCID 53734739, compound

Product 1

HCID 131712052HCID 131712052, compound

Procedure

540 mg. of 2-methyl-3-(p-hydroxyphenylsulfinyl) pentanoic acid and 7-amino-3-carbamoyloxymethyl-3-cephem-4-carboxylic acid were reacted in the same manner as described in Example 28 and 144 mg. of 7-[2-methyl-3-(p-hydroxyphenylsulfinyl)pentanamido]-3-carbamoyloxymethyl-3-cephem-4-carboxylic acid were obtained.

Sources & evidence

ORD record
ord-255e8ed9668f47ed8dc995159c8f6eaa
Source dataset
uspto-grants-1981_01
Patent number
US04245107

Reaction notes

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