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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1389621Generated: October 26, 2026

Methyl 2-phenylthio-2-(3-phenoxyphenyl)propionate → Methyl 2-(3-phenoxyphenyl)propanoate

https://huagongshe.com/reaction/1389621

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-phenylthio-2-(3-phenoxyphenyl)propionateHCID 20556693—
CatalystZincHCID 23994—
SolventAcetic AcidHCID 176—
SolventEthyl AcetateHCID 8857—
ProductMethyl 2-(3-phenoxyphenyl)propanoateHCID 529082—

Reaction Steps

330 mg of methyl 2-phenylthio-2-(3-phenoxyphenyl)propionate obtained in Example 8 was dissolved in 2 ml of acetic acid and the solution was heated while refluxing for 1 hour in the presence of 300 mg of zinc powder. After allowing the reaction mixture to cool, it was diluted with ethyl acetate and the remaining zinc powder was removed by filtration. The filtrate was concentrated to obtain methyl 2-(3-phenoxyphenyl)propionate in a quantative yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04245108
Source datasetuspto-grants-1981_01
ORD IDord-5b4fc6e5ef894abcaba4e4bebf9fa3e2
Source noteuspto-grants-1981_01