Acetyl chloride → HCID 20295047, compound

HRID 1389714Notes

Reaction equation

HRID 1389714 reaction equation
C([Cl:4])(=O)C.S(Cl)(Cl)=O.[CH3:9][O:10][CH:11](OC)[C:12]1[CH:17]=[CH:16][C:15]([Cl:18])=[C:14]([Cl:19])[CH:13]=1>>[Cl:19][C:14]1[CH:13]=[C:12]([CH:17]=[CH:16][C:15]=1[Cl:18])[CH:11]([Cl:4])[O:10][CH3:9]

Participants

4

Reactant 3

HCID 6367Acetyl chlorideHCID 24386Thionyl ChlorideHCID 20295056HCID 20295056, compound

Product 1

HCID 20295047HCID 20295047, compoundYield 99.8%

Procedure

A mixture of acetyl chloride (77 g) and thionyl chloride (0.8 ml) was added, with stirring, to 3,4-dichlorobenzaldehyde dimethyl acetal (110 g). The mixture was kept at laboratory temperature (about 27° C.) for 22 hours and then evaporated at 30° C. under reduced pressure (0.15 mm Hg) for about 4 hours until constant in weight. 3,4-Dichloro-α-methoxybenzyl chloride (112 g) was thus obtained as an oil, which was used without further purification as a starting material in the above preparations.

Workup

  1. additionwas added
  2. customevaporated at 30° C. under reduced pressure (0.15 mm Hg) for about 4 hours until constant in weight

Sources & evidence

ORD record
ord-c337d5b536a54edd9dcc38742808b91f
Source dataset
uspto-grants-1981_01
Patent number
US04246021

Reaction notes

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