HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 13424557, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Cyclohexylamine | HCID 7965 | — |
| Reactant | (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal | HCID 107526 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 13424557 | HCID 13424557 | — |
Reaction Steps
18 G. of D-glucose, 9.9 g. of cyclohexylamine and 1 g. of Raney Nickel in 140 ml. of methanol and 40 ml. of water are treated with hydrogen at 160 psi for 2 hours at 60° C. The solution is filtered to remove the catalyst, and stored overnight at -10° C. to give a precipitate which is recovered by filtration. 2.35 G. of N-cyclohexyl-D-glucamine [m.p. 144°-146° C.; [α]D -20.4° (dimethylsulfoxide)] is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04246193 |
| Source dataset | uspto-grants-1981_01 |
| ORD ID | ord-7772758ec7134f92af88df889135954a |
| Source note | uspto-grants-1981_01 |