HCID 20295355, compound → HCID 20295348, compound

HRID 1389766Notes

Reaction equation

HRID 1389766 reaction equation
[BrH:1].O[CH2:3][CH2:4][O:5][C:6]1[CH:7]=[CH:8][NH:9][CH:10]=[CH:11][CH:12]=1>C(Cl)(Cl)Cl.P(Br)(Br)Br>[BrH:1].[Br:1][CH2:3][CH2:4][O:5][C:6]1[CH:7]=[CH:8][NH:9][CH:10]=[CH:11][CH:12]=1

Participants

4

Reactant 1

HCID 20295355HCID 20295355, compound

Product 1

HCID 20295348HCID 20295348, compound

Reagents, catalysts & solvents 2

HCID 6212ChloroformSolventHCID 24614Phosphorus tribromideSolvent

Procedure

To a suspension of (C) (8 g) in dry chloroform, phosphorous tribromide (8 ml) was added. The mixture was stirred for 24 hours at room temperature. The solvent was stripped in vacuo, and the residue was triturated with five 50 ml portions of dry ether, and finally dried in vacuo to give (D) as a viscous oil.

Workup

  1. additionwas added
  2. customthe residue was triturated with five 50 ml portions of dry ether
  3. customfinally dried in vacuo

Sources & evidence

ORD record
ord-ec0b3b5e4eb341cbb425c4fbf2f8af77
Source dataset
uspto-grants-1981_01
Patent number
US04246262

Reaction notes

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