HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(4-Fluorobenzoyl)propyl chloride → alpha-Phenyl-4-[(3-ethoxy-2-naphthyl)methyl]-1-piperidinepropanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(4-Fluorobenzoyl)propyl chloride | HCID 19750 | — |
| Reactant | 3-Bromo-1-phenylpropan-1-OL | HCID 13561298 | — |
| Reactant | 4-[(3-Ethoxy-2-naphthyl)methyl]piperidine | HCID 20295597 | — |
| Reactant | 6-Chloro-2-naphthyl 4-piperidyl ketone | HCID 54320026 | — |
| Product | alpha-Phenyl-4-[(3-ethoxy-2-naphthyl)methyl]-1-piperidinepropanol | HCID 20295581 | — |
Reaction Steps
When in the procedure of Example 25, 4-[(3-ethoxy-2-naphthyl)methyl]piperidine is substituted for 6-chloro-2-naphthyl 4-piperidyl ketone and 3-bromo-1-phenylpropanol substituted for 4-chloro-1-(4-fluorophenyl)-1-butanone, α-phenyl-4-[(3-ethoxy-2-naphthyl)methyl]-1-piperidinepropanol is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04246268 |
| Source dataset | uspto-grants-1981_01 |
| ORD ID | ord-aad2b903c1e94e87a7f93cbe819daaf4 |
| Source note | uspto-grants-1981_01 |