HuagongsheHuagongshe Chemistry Print Report · For research reference only
4'-Fluorobutyrophenone → alpha-Phenyl-4-[(4-chloro-1-naphthyl)methyl]-1-piperidinebutanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4'-Fluorobutyrophenone | HCID 68498 | — |
| Reactant | 4-[4-((4-Chloro-1-naphthyl)methyl)-1-piperidyl]-1-phenyl-1-butanone hydrochloride | HCID 20295583 | — |
| Product | alpha-Phenyl-4-[(4-chloro-1-naphthyl)methyl]-1-piperidinebutanol | HCID 20295601 | — |
Reaction Steps
When the procedure of Example 37, 4-[4-((4-chloro-1-naphthyl)methyl)-1-piperidyl]-1-phenyl-1-butanone hydrochloride is substituted for 4-[4-(2-naphthyl)hydroxymethyl)-1-piperidyl]-1-(4-fluorophenyl)-1-butanone, α-phenyl-4-[(4-chloro-1-naphthyl)methyl]-1-piperidinebutanol is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04246268 |
| Source dataset | uspto-grants-1981_01 |
| ORD ID | ord-95c4002dd6d44bc5877b75334eff53d4 |
| Source note | uspto-grants-1981_01 |