HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Aminopyridine → HCID 178508797, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Aminopyridine | HCID 10009 | — |
| Reactant | methyl N-(3,5-diamino-6-chloropyrazine-2-carbonyl)carbamimidothioate;hydroiodide | HCID 140329753 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 178508797 | HCID 178508797 | — |
Reaction Steps
1-(3,5-Diamino-6-chloropyrazinoyl)-2-methyl-2-thiopseudourea hydroiodide (970 mg., 0.0025 mole) is added to a solution of 3-aminopyridine (940 mg., 0.01 mole) in dry tetrahydrofuran (20 ml.) and the mixture is heated at reflux for 2 hours, then added to crushed ice-water (200 ml.) to precipitate 423 mg. of 3,5-diamino-6-chloro-N-[(3-pyridylamino)aminomethylene]2-pyrazinecarboxamide hemihydrate, m.p. 220°-2° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04246406 |
| Source dataset | uspto-grants-1981_01 |
| ORD ID | ord-ce28d936c36f4f3d92d6f4020745d840 |
| Source note | uspto-grants-1981_01 |