HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → HCID 54344434, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | 3-Pyridinecarbonyl chloride, hydrochloride (1:1) | HCID 88438 | — |
| Reactant | HCID 86737448 | HCID 86737448 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 54344434 | HCID 54344434 | — |
Reaction Steps
Equimolar amounts of 17-cyclopropylmethyl-7,7-dimethyl-3-hydroxy-6-oxamorphinan (XIV, prepared in Example 5), nicotinoyl chloride hydrochloride and pyridine are mixed together in dry methylene chloride and heated at reflux temperature for 3 hours to produce the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04246413 |
| Source dataset | uspto-grants-1981_01 |
| ORD ID | ord-f57fc05158d443649b199b07ca1da8a0 |
| Source note | uspto-grants-1981_01 |