反应详情

To a stirred solution of 34 parts of (±)-2-(2,6-dichlorophenyl)-N-(2-naphthyl)glycine in 480 parts of ether is added a solution of 13.2 parts of (-)-α-methylbenzylamine in 80 parts of ether at room temperature. The precipitated product is filtered off and crystallized several times from acetonitrile, till a constant rotation, yielding 0.6 parts of (-)-2-(2,6-dichlorophenyl)-N-(2-naphthyl)glycine (-)α-methylbenzylamine salt; mp. 152.7° C.; αD20 -147.6° (1% in chloroform).

1. filtrationThe precipitated product is filtered off
2. customcrystallized several times from acetonitrile