2,5-Hexanedione → HCID 23275889, compound

HRID 1389999Notes

Reaction equation

HRID 1389999 reaction equation
Cl.Cl.[CH3:3][CH:4]1[CH2:9][N:8]([C:10]2[N:15]=[N:14][C:13]([NH:16][NH2:17])=[CH:12][CH:11]=2)[CH2:7][CH:6]([CH3:18])[O:5]1.C([O-])(=O)C.[Na+].[CH3:24][C:25](=O)[CH2:26][CH2:27][C:28](=O)[CH3:29]>C(O)(=O)C>[CH3:3][CH:4]1[CH2:9][N:8]([C:10]2[N:15]=[N:14][C:13]([NH:16][N:17]3[C:28]([CH3:29])=[CH:27][CH:26]=[C:25]3[CH3:24])=[CH:12][CH:11]=2)[CH2:7][CH:6]([CH3:18])[O:5]1

Participants

5

Reactant 3

HCID 80352,5-HexanedioneHCID 517045Sodium AcetateHCID 20294663HCID 20294663, compound

Product 1

HCID 23275889HCID 23275889, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

The compound is prepared according to the procedure of example 2 by contacting 3.8 g (12.8 m moles) of 6-(2,6-dimethyl-morpholino)-3-hydrazino-pyridazine dihydrochloride (prepared according to the procedure described in U.K. Pat. No. 1.157.642; m.p. 217°-220° C.), 2.2 g (25.6 m moles) of sodium acetate and 1.61 g (14.1 m moles) of 2,5-hexanedione in 20 ml of acetic acid. The yield is 1.8 g (47%) of the product of the title which melts at 147°-148° C. when crystallized from ethyl ether.

Workup

  1. customThe compound is prepared
  2. customprepared
  3. customThe yield is 1.8 g (47%) of the product of the title which melts at 147°-148° C. when crystallized from ethyl ether

Sources & evidence

ORD record
ord-4cf9482be0e54aa183fa334a66f2d86c
Source dataset
uspto-grants-1981_01
Patent number
US04247551

Reaction notes

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