2,5-Hexanedione → HCID 20294656, compound

HRID 1390000Notes

Reaction equation

HRID 1390000 reaction equation
[NH:1]([C:3]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[C:6]([N:13]2[CH2:18][CH2:17][O:16][CH2:15][CH2:14]2)=[N:5][N:4]=1)[NH2:2].[CH3:19][C:20](=O)[CH2:21][CH2:22][C:23](=O)[CH3:24]>C(O)(=O)C>[CH3:24][C:23]1[N:2]([NH:1][C:3]2[C:12]3[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=3)[C:6]([N:13]3[CH2:14][CH2:15][O:16][CH2:17][CH2:18]3)=[N:5][N:4]=2)[C:20]([CH3:19])=[CH:21][CH:22]=1

Participants

4

Reactant 2

HCID 80352,5-HexanedioneHCID 20294659HCID 20294659, compound

Product 1

HCID 20294656HCID 20294656, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Conditions

Temperature
65 °C

Procedure

To 4.9 grams (20 m moles) of 1-hydrazino-4-morpholino phthalazine (prepared from 1,4-dichlorophthalazine) according to the procedure of U.K. Pat. No. 1.157.642; M.p. 255°-260° C.) dissolved in 30 ml of acetic acid, 2.74 g (24 m moles) of 2,5-hexanedione are added and the mixture is heated at 65° C. for 3 hours.

Sources & evidence

ORD record
ord-661b9ec5571a4a60a70c898f36619701
Source dataset
uspto-grants-1981_01
Patent number
US04247551

Reaction notes

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