HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,5-Hexanedione → N-(2,5-Dimethyl-1H-pyrrol-1-yl)-6-(1-piperazinyl)-3-pyridazinamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,5-Hexanedione | HCID 8035 | — |
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | HCID 20294650 | HCID 20294650 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | N-(2,5-Dimethyl-1H-pyrrol-1-yl)-6-(1-piperazinyl)-3-pyridazinamine | HCID 23275383 | — |
Reaction Steps
A mixture of 9.2 g (40 m moles) of 3-hydrazino-6-(1-piperazinyl)-pyridazine hydrochloride (m.p. 257° C.; prepared according to the procedure of U.K. Pat. No. 1.157.642), 3.28 g (40 m moles) of ethyl acetate and 4.82 g of 2,5-hexanedione in 100 ml of acetic acid is heated at 75° C. for 2 hours and then allowed to stand for two days at room temperature.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04247551 |
| Source dataset | uspto-grants-1981_01 |
| ORD ID | ord-834435c1ed5d49aabe62b7988fdc8773 |
| Source note | uspto-grants-1981_01 |