HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1390017Generated: November 2, 2026
Ethyl chloroformate → HCID 178464038, compound
https://huagongshe.com/reaction/1390017
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethyl chloroformate | HCID 10928 | — |
| Reactant | HCID 20294747 | HCID 20294747 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 178464038 | HCID 178464038 | — |
Reaction Steps
The filtrated hydrogenation solution from 28 grams of 2-(diethylaminoethylamino)-3-nitro-6-methoxypyridine in 450 ml of dioxane (10 grams Raney nickel, 50 bar and 65° C.) were treated under stirring with 11.25 grams of ethyl chloroformate. After 3 hours stirring the open carbethoxy compound was filtered off and heated to 180° C. under stirring and held at this temperature for one hour. The cooled melt was recrystallized from isopropanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04247556 |
|---|
| Source dataset | uspto-grants-1981_01 |
|---|
| ORD ID | ord-f2b57d6605a64eed8f2ee020d2c3959d |
|---|
| Source note | uspto-grants-1981_01 |
|---|
