Phenol → 2-Chloro-4,6-diphenoxy-1,3,5-triazine

Participants

Reaction Steps

To a solution of 18.4 g (0.1 mole) of cyanuric chloride in 90 ml of acetone was added dropwise a solution of 19.0 g (0.2 moles) of phenol and 8.0 g (0.2 moles) of sodium hydroxide in 75 ml of water at a reaction temperature in the range of 15° to 20° C. After 41/2 hours the precipitate formed was removed by suction, washed with water and dried (with Mg SO4). Purification by recrystallization from n-heptane gave 24.7 g of 2,4-diphenoxy-6-chloro-s-triazine in 82% yield. The melting point was 119°-121° C.

Provenance & Evidence