HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → [6,7-Dichloro-1-oxo-2-(p-chlorophenyl)-2-propargyl-5-indanyloxy]acetic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Ethyl [6,7-dichloro-1-oxo-2-(p-chlorophenyl)-2-(3-(trimethylsilyl)-2-propynyl)-5-indanyloxy]acetate | HCID 12774093 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | [6,7-Dichloro-1-oxo-2-(p-chlorophenyl)-2-propargyl-5-indanyloxy]acetic Acid | HCID 12774095 | — |
Reaction Steps
- Desilylation and hydrolysis of ethyl [6,7-dichloro-1-oxo-2-(p-chlorophenyl)-2-(3-(trimethylsilyl)-2-propynyl)-5-indanyloxy]acetate with sodium hydroxide in ethanol according to the procedure of Example 1, STEP (c), affords the title compound, m.p. 200°-201°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04247715 |
| Source dataset | uspto-grants-1981_01 |
| ORD ID | ord-e1536e90f0a4426b8171d69ee7f393d6 |
| Source note | uspto-grants-1981_01 |