3,4-Dichloroaniline → N-(3,4-dichlorophenyl)dimethyl-maleimide

HRID 1390166ノート

反応式

HRID 1390166 の反応式
[CH3:1][C:2]1=[C:3]([CH3:9])[C:4]([O:6][C:7]1=O)=[O:5].[Cl:10][C:11]1[CH:12]=[C:13]([CH:15]=[CH:16][C:17]=1[Cl:18])[NH2:14]>>[Cl:10][C:11]1[CH:12]=[C:13]([N:14]2[C:7](=[O:6])[C:2]([CH3:1])=[C:3]([CH3:9])[C:4]2=[O:5])[CH:15]=[CH:16][C:17]=1[Cl:18]

参加物

3

反応物 2

HCID 72573,4-DichloroanilineHCID 13010Dimethylmaleic anhydride

生成物 1

HCID 23343685N-(3,4-dichlorophenyl)dimethyl-maleimide

実験手順

In a manner analogous to that of Example 2, 26.2 g (0.2 mole) of dimethylmaleic acid anhydride and 32.6 g (0.2 mole) of 3,4-dichloroaniline are condensed to give N-(3,4-dichlorophenyl)dimethyl-maleimide, which is then dissolved in 300 ml of methanol. To this solution is slowly added in portions, with stirring, 10.8 g of sodium borohydride. After the addition is complete and the generation of gas has subsided, the reaction mixture is poured into ice water. The white precipitate is filtered off, washed with methanol and dried. There is obtained 49.3 g (84% of theory) of the above product in the form of colourless crystalline powder, m.p. 188°.

後処理

  1. customcondensed

出典と根拠

ORDレコード
ord-be6561a17d664b8dbb126319d86adec5
出典データセット
uspto-grants-1979_02
特許番号
US04138243

反応ノート

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