Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dabco | HCID 9237 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 3-[2,4-Bis(2-methylbutan-2-yl)phenoxy]propan-1-amine | HCID 13742088 | — |
| Reactant | HCID 22748385 | HCID 22748385 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | HCID 22748384 | HCID 22748384 | — |
Reaction Steps
A mixture of 23.2 g of Intermediate 1 prepared above, 18 g of thionyl chloride, and 100 ml of benzene was stirred for 3 hours at 40-45° C and after adding to the mixture a solution of 60 g of -(2,4-di-tert-amylphenoxy)propylamine, 23 g of 1,4-diazabicyclo[2,2,2]octane, and 100 ml of benzene, the resultant mixture was stirred for 2 hours to provide the desired product. The solvent used for the recrystallization of the product was methanol. The melting point of the product was 130-131° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04138258 |
|---|
| Source dataset | uspto-grants-1979_02 |
|---|
| ORD ID | ord-08ab0ed122a44f55aa97c78456b0ecb7 |
|---|
| Source note | uspto-grants-1979_02 |
|---|
