HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methylthiazole → 1-(4-Methyl-1,3-thiazol-2-yl)propan-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methylthiazole | HCID 12748 | — |
| Reactant | Propionyl chloride | HCID 62324 | — |
| Reactant | HCID 178418443 | HCID 178418443 | — |
| Product | 1-(4-Methyl-1,3-thiazol-2-yl)propan-1-one | HCID 20560352 | — |
Reaction Steps
b. 4-Methyl-2-propionyl-thiazole was prepared according to the method described in Bull. 20, 702 (1953) by reacting 4-methyl-thiazole with ethyl-magnesium bromide and acylating the obtained Grignard intermediate with propionyl chloride. The product has a b.p. of 83°-88° C./9 mm. Hg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04138410 |
| Source dataset | uspto-grants-1979_02 |
| ORD ID | ord-24d2e05a7d0a402bb5bfdcf6923eb451 |
| Source note | uspto-grants-1979_02 |