HRID1390259

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：NC(=O)CC[C@H](NC(=O)[C@@H]1CCCN1c1ccc([N+](=O)[O-])cc1[N+](=O)[O-])C(=O)NCC(=O)O

HCID90474469

未命名化合物

结构：CC(C)C[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](CCCNC(=N)N[N+](=O)[O-])C(=O)OCc1ccccc1

HCID178446052

未命名化合物

PRODUCTS

生成物

结构：CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1c1ccc([N+](=O)[O-])cc1[N+](=O)[O-])C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](CCCNC(=N)N[N+](=O)[O-])C(=O)OCc1ccccc1

HCID178446025

未命名化合物

PROCEDURE

实验过程

Boc-Leu-Ala-Gly-Gln-D-Arg(NO2)-OBzl (350 mg, 0.45 m mol) was demasked with respect to the N-masking group and coupled with DNP-Pro-Gln-Gly-OH (210 mg, 0.45 m mol) in the manner similar to that of Example 1, paragraph 7).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-86513043c6e94ff880b19aa16698ee16
来源数据集: uspto-grants-1979_02
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04138394
来源说明: uspto-grants-1979_02

反应 SMILES

[NH:1]([C:49](OC(C)(C)C)=[O:50])[C@H:2]([C:7]([NH:9][C@H:10]([C:12]([NH:14][CH2:15][C:16]([NH:18][C@H:19]([C:25]([NH:27][C@@H:28]([C:39]([O:41][CH2:42][C:43]1[CH:48]=[CH:47][CH:46]=[CH:45][CH:44]=1)=[O:40])[CH2:29][CH2:30][CH2:31][NH:32][C:33](=[NH:38])[NH:34][N+:35]([O-:37])=[O:36])=[O:26])[CH2:20][CH2:21][C:22](=[O:24])[NH2:23])=[O:17])=[O:13])[CH3:11])=[O:8])[CH2:3][CH:4]([CH3:6])[CH3:5].[N:56]1([C:77]2[CH:88]=[CH:87][C:83]([N+:84]([O-:86])=[O:85])=[CH:82][C:78]=2[N+:79]([O-:81])=[O:80])[CH2:76][CH2:75][CH2:74][C@H:57]1C(N[C@H](C(NCC(O)=O)=O)CCC(=O)N)=O>>[N:56]1([C:77]2[CH:88]=[CH:87][C:83]([N+:84]([O-:86])=[O:85])=[CH:82][C:78]=2[N+:79]([O-:81])=[O:80])[CH2:76][CH2:75][CH2:74][C@H:57]1[C:16]([NH:18][C@H:19]([C:25]([NH:27][CH2:28][C:49]([NH:1][C@H:2]([C:7]([NH:9][C@H:10]([C:12]([NH:14][CH2:15][C:16]([NH:18][C@H:19]([C:25]([NH:27][C@@H:28]([C:39]([O:41][CH2:42][C:43]1[CH:48]=[CH:47][CH:46]=[CH:45][CH:44]=1)=[O:40])[CH2:29][CH2:30][CH2:31][NH:32][C:33](=[NH:38])[NH:34][N+:35]([O-:37])=[O:36])=[O:26])[CH2:20][CH2:21][C:22](=[O:24])[NH2:23])=[O:17])=[O:13])[CH3:11])=[O:8])[CH2:3][CH:4]([CH3:6])[CH3:5])=[O:50])=[O:26])[CH2:20][CH2:21][C:22](=[O:24])[NH2:23])=[O:17]