HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Phenylindole → 3-phenyl-2,3-dihydro-1H-indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Phenylindole | HCID 96502 | — |
| Reactant | Trifluoroborane Hydrofluoride | HCID 9855450 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3-phenyl-2,3-dihydro-1H-indole | HCID 10932353 | 47% |
Reaction Steps
A mixture of 4.0 g of 3-phenylindole, 80 ml of 86% ethanol, 35 ml of 48% hydrofluoroboric acid and 0.25 g of 10% Pd/C was hydrogenated at 60 p.s.i. and 60° C. for 18 hours. The reaction mixture was worked up as in Example 2 and 1.9 g of pure 3-phenylindoline was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04138494 |
| Source dataset | uspto-grants-1979_02 |
| ORD ID | ord-0ac77e5848c74cbfadec681fa9355a10 |
| Source note | uspto-grants-1979_02 |