HRID1390439

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID75938

Cyclohexanecarbonyl chloride

C7H11ClO

HCID20535272

未命名化合物

结构：CCCCCCC1CC1C(=O)Oc1ccc(C(=O)CNC(C)(C)C)cc1OC(=O)C1CC1CCCCCC

HCID20535377

未命名化合物

PRODUCTS

生成物

HCID70552344

未命名化合物

PROCEDURE

实验过程

When 2-hexylcyclopropanecarbonyl chloride is substituted for the cyclohexanecarbonyl chloride in the procedure described in Example 15A above, the acylation product obtained is 3,4-bis(2-hexylcyclopropanecarbonyloxy)phenyl tert-butylaminomethyl ketone; and when this product is catalytically hydrogenated using the procedure described in Example 15B above, there is obtained 3,4-bis(2-hexylcyclopropanecarbonyloxy)-alpha-(tert-butylaminomethyl)benzyl alcohol.

WORKUP

后处理

customobtained

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-232e27ba2f8e43ed9e0713808f5283e8
来源数据集: uspto-grants-1979_02
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04138581
来源说明: uspto-grants-1979_02

反应 SMILES

C(C1CC1C(Cl)=O)CCCCC.C1(C(Cl)=O)CCCCC1.[C:22]([NH:26][CH2:27][C:28]([C:30]1[CH:35]=[CH:34][C:33]([O:36][C:37]([CH:39]2[CH2:41][CH:40]2[CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH3:47])=[O:38])=[C:32]([O:48][C:49]([CH:51]2[CH2:53][CH:52]2[CH2:54][CH2:55][CH2:56][CH2:57][CH2:58][CH3:59])=[O:50])[CH:31]=1)=[O:29])([CH3:25])([CH3:24])[CH3:23]>>[CH2:54]([CH:52]1[CH2:53][CH:51]1[C:49]([O:48][C:32]1[CH:31]=[C:30]([CH:35]=[CH:34][C:33]=1[O:36][C:37]([CH:39]1[CH2:41][CH:40]1[CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH3:47])=[O:38])[CH:28]([OH:29])[CH2:27][NH:26][C:22]([CH3:25])([CH3:24])[CH3:23])=[O:50])[CH2:55][CH2:56][CH2:57][CH2:58][CH3:59]