Cyclohexanecarbonyl chloride → HCID 70552344, compound

HRID 1390439Notes

Reaction equation

C(C1CC1C(Cl)=O)CCCCC.C1(C(Cl)=O)CCCCC1.[C:22]([NH:26][CH2:27][C:28]([C:30]1[CH:35]=[CH:34][C:33]([O:36][C:37]([CH:39]2[CH2:41][CH:40]2[CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH3:47])=[O:38])=[C:32]([O:48][C:49]([CH:51]2[CH2:53][CH:52]2[CH2:54][CH2:55][CH2:56][CH2:57][CH2:58][CH3:59])=[O:50])[CH:31]=1)=[O:29])([CH3:25])([CH3:24])[CH3:23]>>[CH2:54]([CH:52]1[CH2:53][CH:51]1[C:49]([O:48][C:32]1[CH:31]=[C:30]([CH:35]=[CH:34][C:33]=1[O:36][C:37]([CH:39]1[CH2:41][CH:40]1[CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH3:47])=[O:38])[CH:28]([OH:29])[CH2:27][NH:26][C:22]([CH3:25])([CH3:24])[CH3:23])=[O:50])[CH2:55][CH2:56][CH2:57][CH2:58][CH3:59]

Participants

Reactant 3

HCID 75938Cyclohexanecarbonyl chloride

HCID 20535272HCID 20535272, compound

HCID 20535377HCID 20535377, compound

Product 1

HCID 70552344HCID 70552344, compound

Procedure

When 2-hexylcyclopropanecarbonyl chloride is substituted for the cyclohexanecarbonyl chloride in the procedure described in Example 15A above, the acylation product obtained is 3,4-bis(2-hexylcyclopropanecarbonyloxy)phenyl tert-butylaminomethyl ketone; and when this product is catalytically hydrogenated using the procedure described in Example 15B above, there is obtained 3,4-bis(2-hexylcyclopropanecarbonyloxy)-alpha-(tert-butylaminomethyl)benzyl alcohol.

Workup

customobtained

Sources & evidence

ORD record: ord-232e27ba2f8e43ed9e0713808f5283e8
Source dataset: uspto-grants-1979_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04138581

Reaction notes

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