Cyclohexanecarbonyl chloride → HCID 57263033, compound

HRID 1390445Notes

Reaction equation

HRID 1390445 reaction equation
CC1CCCC(CC(Cl)=O)CC1.C1(C(Cl)=O)CCCCC1.[C:22]([NH:26][CH2:27][C:28]([C:30]1[CH:35]=[CH:34][C:33]([O:36][C:37](=[O:47])[CH2:38][CH:39]2[CH2:45][CH2:44][CH2:43][CH:42]([CH3:46])[CH2:41][CH2:40]2)=[C:32]([O:48][C:49](=[O:59])[CH2:50][CH:51]2[CH2:57][CH2:56][CH2:55][CH:54]([CH3:58])[CH2:53][CH2:52]2)[CH:31]=1)=[O:29])([CH3:25])([CH3:24])[CH3:23]>>[CH3:58][CH:54]1[CH2:55][CH2:56][CH2:57][CH:51]([CH2:50][C:49]([O:48][C:32]2[CH:31]=[C:30]([CH:35]=[CH:34][C:33]=2[O:36][C:37](=[O:47])[CH2:38][CH:39]2[CH2:45][CH2:44][CH2:43][CH:42]([CH3:46])[CH2:41][CH2:40]2)[CH:28]([OH:29])[CH2:27][NH:26][C:22]([CH3:25])([CH3:23])[CH3:24])=[O:59])[CH2:52][CH2:53]1

Participants

4

Reactant 3

HCID 75938Cyclohexanecarbonyl chlorideHCID 20535279HCID 20535279, compoundHCID 57246065HCID 57246065, compound

Product 1

HCID 57263033HCID 57263033, compound

Procedure

When 4-methylcycloheptaneacetyl chloride is substituted for the cyclohexanecarbonyl chloride in the procedure described in Example 15A above, the acylation product obtained is 3,4-bis(4-methylcycloheptaneacetoxy)phenyl tert-butylaminomethyl ketone; and when this product is catalytically hydrogenated using the procedure described in Example 15B above, there is obtained 3,4-bis(4-methylcycloheptaneacetoxy)-alpha-(tert-butylaminomethyl)benzyl alcohol.

Workup

  1. customobtained

Sources & evidence

ORD record
ord-c33a087b174149bdb6fb715633eba8ba
Source dataset
uspto-grants-1979_02
Patent number
US04138581

Reaction notes

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