HCID 21495456, compound → HCID 70552462, compound

HRID 1390448Notes

Reaction equation

HRID 1390448 reaction equation
CC(C1CC1)C(Cl)=O.[C:9]([NH:13][CH2:14][C:15]([C:17]1[CH:22]=[CH:21][C:20]([O:23][C:24](=[O:30])[CH:25]([CH3:29])[CH:26]2[CH2:28][CH2:27]2)=[C:19]([O:31][C:32](=[O:38])[CH:33]([CH3:37])[CH:34]2[CH2:36][CH2:35]2)[CH:18]=1)=[O:16])([CH3:12])([CH3:11])[CH3:10]>>[CH3:37][CH:33]([CH:34]1[CH2:35][CH2:36]1)[C:32]([O:31][C:19]1[CH:18]=[C:17]([CH:22]=[CH:21][C:20]=1[O:23][C:24](=[O:30])[CH:25]([CH3:29])[CH:26]1[CH2:27][CH2:28]1)[CH:15]([OH:16])[CH2:14][NH:13][C:9]([CH3:12])([CH3:11])[CH3:10])=[O:38]

Participants

3

Reactant 2

HCID 21495456HCID 21495456, compoundHCID 70582738HCID 70582738, compound

Product 1

HCID 70552462HCID 70552462, compound

Procedure

Following the procedure described above in Example 15A using alpha-methylcyclopropaneacetyl chloride instead of cyclohexanecarbonyl chloride the acylation product obtained is 3,4-bis(alpha-methylcyclopropaneacetoxy)phenyl tert-butylaminomethyl ketone; and when this product is catalytically hydrogenated, using the procedure described above in Example 15B, there is obtained 3,4-bis(alpha-methylcyclopropaneacetoxy)-alpha-(tert-butylaminomethyl)benzyl alcohol.

Workup

  1. customobtained

Sources & evidence

ORD record
ord-9b18296b4d8f41a18b7d3088d3e61539
Source dataset
uspto-grants-1979_02
Patent number
US04138581

Reaction notes

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