HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → HCID 12295055, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | p-Anisoyl chloride | HCID 7477 | — |
| Reactant | 1-(3,4-Dihydroxyphenyl)-2-((1,1-dimethylethyl)amino)ethan-1-one hydrochloride | HCID 3015704 | — |
| Reactant | Phenolate Sodium | HCID 4445035 | — |
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Product | HCID 12295055 | HCID 12295055 | — |
Reaction Steps
Proceeding in a manner similar to that described in Example 30A above, 26 g. of 3,4-dihydroxyphenyl tert-butylaminomethyl ketone hydrochloride was reacted with 17 g. of sodium methoxide in 200 ml. of N,N-dimethylformamide, and the resulting sodium phenolate salt was interacted with p-anisoyl chloride to yield 12.3 g of 3,4-bis(p-anisoyloxy)phenyl tert-butylaminomethyl ketone hydrochloride as a white crystalline solid which melted at 205-208° C. (uncorr.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04138581 |
| Source dataset | uspto-grants-1979_02 |
| ORD ID | ord-6c1692ec7c0042eca0f2e82d78ad4feb |
| Source note | uspto-grants-1979_02 |