Heptane → 3-{4-[2-(4-Fluorophenyl)-8-isopropoxyimidazo[1,2-a]pyrazin-3-yl]-pyrimidin-2-ylamino}-2,2-dimethylpropan-1-ol

HRID 139048Notes

Reaction equation

HRID 139048 reaction equation
[CH3:38][CH2:39][CH2:40][CH2:41][CH2:42][CH2:43][CH3:44].[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([cH:12][cH:13][n:14][c:15]3[O:16][CH:17]([CH3:18])[CH3:19])[c:20]2-[c:21]2[n:22][c:23]([S:27]([CH3:28])(=[O:29])=[O:30])[n:24][cH:25][cH:26]2)[cH:6][cH:7]1.[NH2:31][CH2:32][C:33]([CH2:34][OH:35])([CH3:36])[CH3:37]>>[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([cH:12][cH:13][n:14][c:15]3[O:16][CH:17]([CH3:18])[CH3:19])[c:20]2-[c:21]2[n:22][c:23]([NH:31][CH2:32][C:33]([CH2:34][OH:35])([CH3:36])[CH3:37])[n:24][cH:25][cH:26]2)[cH:6][cH:7]1

Participants

4

Reactant 3

HCID 8900HeptaneHCID 1173261-Propanol, 3-amino-2,2-dimethyl-HCID 588695382-(4-Fluorophenyl)-8-isopropoxy-3-(2-methanesulfonylpyrimidin-4-yl)-imidazo[1,2-a]pyrazine

Product 1

HCID 160504513-{4-[2-(4-Fluorophenyl)-8-isopropoxyimidazo[1,2-a]pyrazin-3-yl]-pyrimidin-2-ylamino}-2,2-dimethylpropan-1-ol

Sources & evidence

ORD record
ord-bb23fcf3354d49588c4fff4a1f6be8cd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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