1-Nitro-9-phenoxyacridine → HCID 12391509, compound

HRID 1390533Notes

Reaction equation

[N+:1]([C:4]1[C:17]2[C:8](=[N:9][C:10]3[C:15]([C:16]=2OC2C=CC=CC=2)=[CH:14][CH:13]=[CH:12][CH:11]=3)[CH:7]=[CH:6][CH:5]=1)([O-:3])=[O:2].[ClH:25].Cl.[CH2:27]([NH:31][CH2:32][CH2:33][NH2:34])[CH:28]([CH3:30])[CH3:29]>C1(O)C=CC=CC=1>[ClH:25].[ClH:25].[N+:1]([C:4]1[C:17]2[C:8](=[N:9][C:10]3[C:15]([C:16]=2[NH:34][CH2:33][CH2:32][NH:31][CH2:27][CH:28]([CH3:30])[CH3:29])=[CH:14][CH:13]=[CH:12][CH:11]=3)[CH:7]=[CH:6][CH:5]=1)([O-:3])=[O:2]

Participants

Conditions

Temperature: 90 °C

Procedure

1-Nitro-9-phenoxyacridine (1.58 g) is dissolved in about 5 g of phenol, and then 0.95 g of 2-isobutylaminoethylamine dihydrochloride is added and is heated at a temperature of 90° C. for 1.2 hour. It is isolated in a similar manner, as in Example VII. There is obtained 1-nitro-9-isobutylaminoethylaminoacridine dihydrochloride with a melting point of 230° C. (with decomposition).

Workup

customIt is isolated in a similar manner, as in Example VII

Sources & evidence

ORD record: ord-5b679c64b23c4fb283e4da3038897f60
Source dataset: uspto-grants-1979_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04139531

Reaction notes

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