HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Sodium hydride → 6-(2-Benzylamino-2,2-dimethylethoxy)-nicotinic acid amide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Sodium hydride | HCID 24758 | — |
| Edukt | 6-Chloronicotinamide | HCID 80456 | — |
| Edukt | 2-(Benzylamino)-2-methylpropan-1-ol | HCID 962368 | — |
| Lösungsmittel | Dimethylformamide | HCID 6228 | — |
| Produkt | 6-(2-Benzylamino-2,2-dimethylethoxy)-nicotinic acid amide | HCID 53961034 | — |
Reaktionsschritte
Reaction of 47 g of 2-benzylamino-2-methyl-1-propanol, 13.3 g of sodium hydride dispersion and 23.5 g of 6-chloronicotinic acid amide in 300 ml of dimethylformamide analogously to Example 1 a) gives 6-(2-benzylamino-2,2-dimethyl-ethoxy)-nicotinic acid amide of melting point 125°-126° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04139623 |
| Quelldatensatz | uspto-grants-1979_02 |
| ORD ID | ord-290c21cb1e7d42f29d79c68a94cdff42 |
| Quellennotiz | uspto-grants-1979_02 |