HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 2-(((5-Methyl-1H-imidazol-4-yl)methyl)thio)ethylamine dihydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Cysteamine Hydrochloride | HCID 9082 | — |
| Reactant | 4-(methoxymethyl)-5-methyl-3H-imidazole | HCID 12362436 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 2-(((5-Methyl-1H-imidazol-4-yl)methyl)thio)ethylamine dihydrochloride | HCID 3015999 | 80% |
Reaction Steps
4-Methoxymethyl-5-methylimidazole as the hydrochloride (4.5 g, 0.03 mole) and 3.4 g (0.03 mole) of cysteamine hydrochloride were dissolved in a minimum amount of acetic acid and the mixture was refluxed for 18 hours. After cooling in an ice bath, the mixture was filtered to give 5.8 g (80%) of 4-(2-aminoethyl)thiomethyl-5-methylimidazole dihydrochloride salt (thioamine salt).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04139708 |
| Source dataset | uspto-grants-1979_02 |
| ORD ID | ord-ae31e08d9c8745538d40b3617de61a84 |
| Source note | uspto-grants-1979_02 |