HCID 12803422, compound → 1-(2-Methoxyethyl)-4-phenylimidazolidin-2-one

HRID 1390685Notes

Reaction equation

HRID 1390685 reaction equation
[CH3:1][O:2][CH2:3][CH2:4][N:5]1[CH:9]=[C:8]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[NH:7][C:6]1=[O:16].[H][H]>[Pd].C(O)C>[CH3:1][O:2][CH2:3][CH2:4][N:5]1[CH2:9][CH:8]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[NH:7][C:6]1=[O:16]

Participants

5

Reactant 2

HCID 12803422HCID 12803422, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 128034231-(2-Methoxyethyl)-4-phenylimidazolidin-2-one

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

Approximately 10.9 g. of 1-(2-methoxyethyl)-4-phenyl-4-imidazolin-2-one and 1 g. of 10% palladium on carbon in 100 ml. of ethanol is hydrogenated in a Parr Shaker apparatus at 30 psig of hydrogen for 45 minutes. The catalyst is filtered, washed with ethanol, and the filtrate is concentrated to give the title compound as a waxy white solid; m.p. 82°-83° C.

Workup

  1. filtrationThe catalyst is filtered
  2. washwashed with ethanol
  3. concentrationthe filtrate is concentrated

Sources & evidence

ORD record
ord-5e499b2515564d97b7405317d52a2f49
Source dataset
uspto-grants-1979_02
Patent number
US04139707

Reaction notes

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