HuagongsheHuagongshe Chemistry Print Report · For research reference only
19-Hydroxy-1alpha-methyl-4-androsten-3,17-dione propionate → 17beta,19-Dihydroxy-1alpha,6alpha-dimethyl-4-androsten-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 19-Hydroxy-1alpha-methyl-4-androsten-3,17-dione propionate | HCID 86734730 | — |
| Reactant | 17beta,19-Dihydroxy-1alpha,7alpha-dimethyl-4-androsten-3-one dipropionate | HCID 86734731 | — |
| Reactant | 17beta,19-Dihydroxy-1alpha,6alpha-dimethyl-4-androsten-3-one dipropionate | HCID 86735690 | — |
| Product | 17beta,19-Dihydroxy-1alpha,6alpha-dimethyl-4-androsten-3-one | HCID 70583937 | — |
| Product | 19-Hydroxy1alpha-methyl-4-androstene-3,17-dione | HCID 70584008 | — |
| Product | 17beta,19-Dihydroxy-1alpha,7alpha-dimethyl-4-androsten-3-one | HCID 70585453 | — |
Reaction Steps
Substituting 17β,19-dihydroxy-1α,7α-dimethyl-4-androsten-3-one dipropionate, 17β,19-dihydroxy-1α,6α-dimethyl-4-androsten-3-one dipropionate, 19-hydroxy-1α-methyl-4-androsten-3,17-dione propionate and 17β,19-dihydroxy-1α,7α-dimethyl-4-androsten-3-one dipropionate in the above procedure results in the preparation of 17β,19-dihydroxy-1α,17α-dimethyl-4-androsten-3-one, 17β,19-dihydroxy-1α,6α-dimethyl-4-androsten-3-one, 19-hydroxy-1α-methyl-4-androstene-3,17-dione and 17β,19-dihydroxy-1α,7α-dimethyl-4-androsten-3-one, respectively.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04139617 |
| Source dataset | uspto-grants-1979_02 |
| ORD ID | ord-fffd0430283f43d781e50c9ea69775f8 |
| Source note | uspto-grants-1979_02 |