17beta,19-Dihydroxy-1alpha,7alpha-dimethyl-5-androsten-3-one diacetate → 5-Androstene-17beta,19-diol 19-acetate

HRID 1390766Notes

Reaction equation

HRID 1390766 reaction equation
[C:1]([OH:4])(=[O:3])[CH3:2].O[CH2:6][C@@:7]12[C@@H:24]3[C@H:15]([C@H:16]4[C@@:20]([CH2:22][CH2:23]3)([CH3:21])[C:19](=[O:25])[CH2:18][CH2:17]4)[CH2:14][CH:13]=[C:12]1[CH2:11][CH2:10][CH2:9][CH2:8]2.C(O)(=O)C.C(O)(=O)C.O[C@H]1CC[C@H]2[C@H]3[C@H](CC[C@]12C)[C@]1(CO)C(CC(=O)C[C@@H]1C)=C[C@H]3C>>[C:1]([O:4][CH2:6][C@@:7]12[C@@H:24]3[C@H:15]([C@H:16]4[C@@:20]([CH2:22][CH2:23]3)([CH3:21])[C@@H:19]([OH:25])[CH2:18][CH2:17]4)[CH2:14][CH:13]=[C:12]1[CH2:11][CH2:10][CH2:9][CH2:8]2)(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 8673631317beta,19-Dihydroxy-1alpha,7alpha-dimethyl-5-androsten-3-one diacetateHCID 8673631419-Hydroxy-5-androsten-17-one acetate

Product 1

HCID 706053975-Androstene-17beta,19-diol 19-acetate

Procedure

Substituting 19-hydroxy-5-androsten-17-one acetate for the 17β,19-dihydroxy-1α,7α-dimethyl-5-androsten-3-one diacetate above, results in the formation of 5-androstene-17β,19-diol 19-acetate.

Sources & evidence

ORD record
ord-23aa3b69055a469d93ee02f2d19c959f
Source dataset
uspto-grants-1979_02
Patent number
US04139617

Reaction notes

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