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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1390777Generated: October 27, 2026

(8R,9S,10S,13S,14S)-10-(hydroxymethyl)-13-methyl-3,4,7,8,9,10,11,12,13,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17(2H)-one → 19-Triphenylsiloxy-5-androsten-17-one

https://huagongshe.com/reaction/1390777

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(8R,9S,10S,13S,14S)-10-(hydroxymethyl)-13-methyl-3,4,7,8,9,10,11,12,13,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17(2H)-oneHCID 10334324—
Reactant19-Triphenylsiloxy-4-androstene-3,17-dioneHCID 22803239—
Product19-Triphenylsiloxy-5-androsten-17-oneHCID 22806907—

Reaction Steps

Substituting 19-hydroxy-5-androsten-17-one for the 19-hydroxy-4-androstene-3,17-dione above results in the formation of 19-triphenylsiloxy-5-androsten-17-one.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04139617
Source datasetuspto-grants-1979_02
ORD IDord-874fa3f68cb744cbb933fd33946bed26
Source noteuspto-grants-1979_02