HCID 7060880, compound → HCID 86736325, compound

HRID 1390784Notes

Reaction equation

HRID 1390784 reaction equation
[C:1]([O:4][C@H]1CC[C@@]2(CO)C(=CC[C@@H]3[C@@H]2CC[C@@]2(C)[C@H]3CC[C@@H]2O)C1)(=[O:3])[CH3:2].[OH:26][C@H:27]1[CH2:44][CH2:43][C@@:42]2([CH2:45][OH:46])[C:29](=[CH:30][CH2:31][C@@H:32]3[C@@H:41]2[CH2:40][CH2:39][C@@:37]2([CH3:38])[C@H:33]3[CH2:34][CH2:35][C:36]2=[O:47])[CH2:28]1>>[C:1]([OH:4])(=[O:3])[CH3:2].[OH:26][C@H:27]1[CH2:44][CH2:43][C@@:42]2([CH:45]=[O:46])[C:29](=[CH:30][CH2:31][C@@H:32]3[C@@H:41]2[CH2:40][CH2:39][C@@:37]2([CH3:38])[C@H:33]3[CH2:34][CH2:35][C:36]2=[O:47])[CH2:28]1

Participants

3

Reactant 2

HCID 7060880HCID 7060880, compoundHCID 23250781HCID 23250781, compound

Product 1

HCID 86736325HCID 86736325, compound

Procedure

Substituting 5-androstene-3β,17β,19-triol 3-acetate and 4α,17α-dimethyl-5-androstene-3β,17β,19-triol for the 3β,19-dihydroxy-5-androsten-17-one above results in the preparation of 3β-hydroxy-5-androstene-17,19-dione acetate and 17β-hydroxy-4α,17α-dimethyl-5-androstene-3,19-dione, respectively.

Sources & evidence

ORD record
ord-5f8d27cbcbe64e15bf85515442c5b7e2
Source dataset
uspto-grants-1979_02
Patent number
US04139617

Reaction notes

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