2,3-Dichloro-5,6-dicyano-1,4-benzoquinone → HCID 12789651, compound

Participants

Reaction Steps

A mixture of 11.0 g (.039 mol) of methyl 2-[5-(2-pyridyl)-2-isoxazolin-3-yl]benzoate and 9.76 g (.043 mol) of 2,3-dichloro-5,6-dicyano-1,4-benzoquinone in 200 ml of chlorobenzene was held at reflux for 3 hours; the mixture was allowed to cool, was filtered, and was concentrated under vacuum to 12.0 g of residue. The residue was chromatographed on 400 g of silica gel with 20% ether in benzene to give 3.8 g (35%) of solid, mp 54-57° C. Recrystallization of a small sample gave solid with mp 58-60.5° C.

Provenance & Evidence