HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 12789649, compound → HCID 12789653, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 12789649 | HCID 12789649 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 12789653 | HCID 12789653 | 99% |
Reaction Steps
A solution of 1.81 g of methyl 2-[5-(4-methoxyphenyl)-3-isoxazolyl]benzoate in 8 ml concentrated HCl and 8 ml of acetic acid was held at reflux for 4 hours, cooled, diluted with water, and filtered to give 1.71 g (99%) of white solid, mp 182-185° C. Recrystallization of the solid from CH3CN gave 1.27 g (73%) of solid, mp 186-187.5° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04140515 |
| Source dataset | uspto-grants-1979_02 |
| ORD ID | ord-885a1c908ee748eaa7416e9e56765326 |
| Source note | uspto-grants-1979_02 |