HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1390970Generated: November 1, 2026
1-(Difluoromethoxy)-4-isocyanatobenzene → HCID 21332243, compound
https://huagongshe.com/reaction/1390970
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1-(Difluoromethoxy)-4-isocyanatobenzene | HCID 2733371 | — |
| Reactant | 1H-Pyrazole, 3,5-bis(4-chlorophenyl)-4,5-dihydro- | HCID 4738351 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 21332243 | HCID 21332243 | 35% |
Reaction Steps
5.55 g (0.03 mol) of 4-difluoromethoxy-phenyl isocyanate in 20 ml of toluene were added, at 50° C., to a solution of 8.74 g (0.03 mol) of 3-(4-chlorophenyl)-5-(4-chlorophenyl)-2-pyrazoline in 100 ml of toluene and the batch was stirred for 2 hours at 80° C. After it had cooled, the product which had precipitated was isolated by filtration. 5 g (35% of theory) of 1-(4-difluoromethoxyphenylcarbamoyl)-3-(4-chlorophenyl)-5-(4-chlorophenyl)-2-pyrazoline of melting point 174° C. were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04140792 |
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| Source dataset | uspto-grants-1979_02 |
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| ORD ID | ord-946fa52f0e644626b95f8d5d0fa3dc16 |
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| Source note | uspto-grants-1979_02 |
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