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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1390978Generated: October 26, 2026

1-(p-Tolyl)-4-(p-nitrobenzyl)piperazine → 1-(p-Tolyl)-4-[(4-aminophenyl)methyl]piperazine

https://huagongshe.com/reaction/1390978

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(p-Tolyl)-4-(p-nitrobenzyl)piperazineHCID 21331867—
Catalysttitanium(III) trichlorideHCID 10313229—
Product1-(p-Tolyl)-4-[(4-aminophenyl)methyl]piperazineHCID 21331844—

Reaction Steps

In the manner given in Example 1B, 1-(p-tolyl)-4-(p-nitrobenzyl)piperazine is reduced with aqueous titanium trichloride to give 1-(p-tolyl)-4-[(4-aminophenyl)methyl]piperazine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04140775
Source datasetuspto-grants-1979_02
ORD IDord-12c744327bfa4ef58e90a3eb4147532f
Source noteuspto-grants-1979_02