HCID 21331879, compound → HCID 21331884, compound

HRID 1390981Notes

Reaction equation

HRID 1390981 reaction equation
[CH2:1]([C:3]1[CH:8]=[CH:7][C:6]([N:9]2[CH2:14][CH2:13][N:12]([CH2:15][C:16]3[CH:21]=[CH:20][C:19]([N+:22]([O-])=O)=[CH:18][CH:17]=3)[CH2:11][CH2:10]2)=[CH:5][CH:4]=1)[CH3:2]>[Cl-].[Cl-].[Cl-].[Ti+3]>[CH2:1]([C:3]1[CH:4]=[CH:5][C:6]([N:9]2[CH2:10][CH2:11][N:12]([CH2:15][C:16]3[CH:21]=[CH:20][C:19]([NH2:22])=[CH:18][CH:17]=3)[CH2:13][CH2:14]2)=[CH:7][CH:8]=1)[CH3:2]

Participants

3

Reactant 1

HCID 21331879HCID 21331879, compound

Product 1

HCID 21331884HCID 21331884, compound

Reagents, catalysts & solvents 1

HCID 10313229titanium(III) trichlorideCatalyst

Procedure

In the manner given in Example 1B, 1-(p-ethylphenyl)-4-(p-nitrobenzyl)piperazine is reduced with aqueous titanium trichloride to give 1-(p-ethylphenyl)-4-[(4-aminophenyl)methyl]piperazine.

Sources & evidence

ORD record
ord-2fe2da1bfb5a4be79fcaf89a937512e2
Source dataset
uspto-grants-1979_02
Patent number
US04140775

Reaction notes

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