HCID 21331815, compound → HCID 21331808, compound

HRID 1390996Notes

Reaction equation

HRID 1390996 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[CH2:13][CH2:12][N:11]([CH2:14][C:15]3[CH:20]=[CH:19][C:18]([N+:21]([O-])=O)=[CH:17][CH:16]=3)[CH2:10][CH2:9]2)=[CH:4][CH:3]=1>[Cl-].[Cl-].[Cl-].[Ti+3]>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([N:8]2[CH2:9][CH2:10][N:11]([CH2:14][C:15]3[CH:20]=[CH:19][C:18]([NH2:21])=[CH:17][CH:16]=3)[CH2:12][CH2:13]2)=[CH:6][CH:7]=1

Participants

3

Reactant 1

HCID 21331815HCID 21331815, compound

Product 1

HCID 21331808HCID 21331808, compound

Reagents, catalysts & solvents 1

HCID 10313229titanium(III) trichlorideCatalyst

Procedure

In the manner given in Example 1B, 1-(4-bromophenyl)- 4-(p-nitrobenzyl)piperazine is reduced with aqueous titanium trichloride to give 1-(4-bromophenyl)-4-[(4-aminophenyl)methyl]piperazine.

Sources & evidence

ORD record
ord-6b0ae65ab8354f149495ebab253cb5e1
Source dataset
uspto-grants-1979_02
Patent number
US04140775

Reaction notes

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