HCID 21331827, compound → HCID 21331880, compound

HRID 1390999Notes

Reaction equation

HRID 1390999 reaction equation
[CH2:1]([O:4][C:5]1[CH:6]=[C:7]([N:15]2[CH2:20][CH2:19][N:18]([CH2:21][C:22]3[CH:27]=[CH:26][C:25]([N+:28]([O-])=O)=[CH:24][CH:23]=3)[CH2:17][CH2:16]2)[CH:8]=[C:9]([O:11][CH2:12][CH2:13][CH3:14])[CH:10]=1)[CH2:2][CH3:3]>[Cl-].[Cl-].[Cl-].[Ti+3]>[CH2:1]([O:4][C:5]1[CH:6]=[C:7]([N:15]2[CH2:16][CH2:17][N:18]([CH2:21][C:22]3[CH:27]=[CH:26][C:25]([NH2:28])=[CH:24][CH:23]=3)[CH2:19][CH2:20]2)[CH:8]=[C:9]([O:11][CH2:12][CH2:13][CH3:14])[CH:10]=1)[CH2:2][CH3:3]

Participants

3

Reactant 1

HCID 21331827HCID 21331827, compound

Product 1

HCID 21331880HCID 21331880, compound

Reagents, catalysts & solvents 1

HCID 10313229titanium(III) trichlorideCatalyst

Procedure

In the manner given in Example 1B, 1-(3,5-dipropoxyphenyl)-4-(p-nitrobenzyl)piperazine is reduced with aqueous titanium trichloride to give 1-(3,5-dipropoxyphenyl)-4-[(4-aminophenyl)methyl]piperazine.

Sources & evidence

ORD record
ord-155c7ee3f2f64e8191a2ab03fe588d83
Source dataset
uspto-grants-1979_02
Patent number
US04140775

Reaction notes

Loading…