1-(4-nitrobenzyl)-4-phenylpiperazine → HCID 23507360, compound

HRID 1391009Notes

Reaction equation

HRID 1391009 reaction equation
[C:1]1([N:7]2[CH2:12][CH2:11][N:10]([CH2:13][C:14]3[CH:19]=[CH:18][C:17]([N+:20]([O-])=O)=[CH:16][CH:15]=3)[CH2:9][CH2:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1>[Cl-].[Cl-].[Cl-].[Ti+3]>[C:1]1([N:7]2[CH2:8][CH2:9][N:10]([CH2:13][C:14]3[CH:15]=[CH:16][C:17]([NH2:20])=[CH:18][CH:19]=3)[CH2:11][CH2:12]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 1

HCID 2594881-(4-nitrobenzyl)-4-phenylpiperazine

Product 1

HCID 23507360HCID 23507360, compound

Reagents, catalysts & solvents 1

HCID 10313229titanium(III) trichlorideCatalyst

Procedure

In the manner given in Example 1B, 1-phenyl-4-(p-nitrobenzyl)piperazine is reduced with aqueous titanium trichloride to give 1-phenyl-4-[(4-aminophenyl)methyl]piperazine.

Sources & evidence

ORD record
ord-4f61b67baa71443e801b798423b6f551
Source dataset
uspto-grants-1979_02
Patent number
US04140775

Reaction notes

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