HCID 21331835, compound → HCID 21331876, compound

HRID 1391015Notes

Reaction equation

HRID 1391015 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([Cl:8])=[CH:4][C:3]=1[N:9]1[CH2:14][CH2:13][N:12]([CH2:15][C:16]2[CH:21]=[CH:20][C:19]([N+:22]([O-])=O)=[CH:18][CH:17]=2)[CH2:11][CH2:10]1>[Cl-].[Cl-].[Cl-].[Ti+3]>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([Cl:8])=[CH:4][C:3]=1[N:9]1[CH2:14][CH2:13][N:12]([CH2:15][C:16]2[CH:21]=[CH:20][C:19]([NH2:22])=[CH:18][CH:17]=2)[CH2:11][CH2:10]1

Participants

3

Reactant 1

HCID 21331835HCID 21331835, compound

Product 1

HCID 21331876HCID 21331876, compound

Reagents, catalysts & solvents 1

HCID 10313229titanium(III) trichlorideCatalyst

Procedure

In the manner given in Example 1B, 1-(2,5-dichlorophenyl)-4-(p-nitrobenzyl)piperazine is reduced with aqueous titanium trichloride to give 1-(2,5-dichlorophenyl)-4-[(4-aminophenyl)methyl]piperazine.

Sources & evidence

ORD record
ord-7d734dffc7854e69b23247f2224bee6e
Source dataset
uspto-grants-1979_02
Patent number
US04140775

Reaction notes

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