HCID 21331809, compound → HCID 21331820, compound

HRID 1391024Notes

Reaction equation

HRID 1391024 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[CH2:13][CH2:12][N:11]([CH:14]([C:16]3[CH:21]=[CH:20][C:19]([N+:22]([O-])=O)=[CH:18][CH:17]=3)[CH3:15])[CH2:10][CH2:9]2)=[CH:4][CH:3]=1>[Cl-].[Cl-].[Cl-].[Ti+3]>[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([N:8]2[CH2:9][CH2:10][N:11]([CH:14]([C:16]3[CH:17]=[CH:18][C:19]([NH2:22])=[CH:20][CH:21]=3)[CH3:15])[CH2:12][CH2:13]2)=[CH:6][CH:7]=1

Participants

3

Reactant 1

HCID 21331809HCID 21331809, compound

Product 1

HCID 21331820HCID 21331820, compound

Reagents, catalysts & solvents 1

HCID 10313229titanium(III) trichlorideCatalyst

Procedure

In the manner given in Example 1B, 1-(p-methylphenyl)-4-[1-(p-nitrophenyl)ethyl]piperazine is reduced with aqueous titanium trichloride to give 1-(p-methylphenyl)-4-[1-(p-aminophenyl)ethyl]piperazine.

Sources & evidence

ORD record
ord-602eee529dbb4e49b10a346295a4f296
Source dataset
uspto-grants-1979_02
Patent number
US04140775

Reaction notes

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